For providers
Provider resources
Resources designed to support your practice
From videos and case studies to patient guides and more, find resources to help you use the Riskguard® test with your patients.
Exact Sciences Provider Hub
Exact Sciences Provider Hub
Submit and track orders, access test results, and more.
Forms and billing resources
Test requisition form
PDF
If you prefer not to order on our Provider Hub, you can download the test requistition form and fax it to +1 715-406-4175. If you are collecting a sample in clinic, include a copy of the order form in the specimen kit.
Billing and coverage info card
PDF
We're here to help. Our support team can help your patients navigate the insurance coverage process.
ICD-10 codes
It is the healthcare provider’s responsibility to select the appropriate diagnosis code. To identify the appropriate ICD-10 code(s), we recommend reviewing the resources posted on the Centers for Medicare & Medicaid Services (CMS) website.
CPT codes
Depending on the diagnosis of cancer in the patient, and any family history of cancer, the procedure codes for the Riskguard® test may differ based upon the cancer indication and payor policy. Patients can contact 866-662-6897, option 2, option 1, to obtain further assistance from the billing team.
Call +1 866-662-6897
Informed consent form
PDF
This form describes the benefits, risks, and limitations of genetic testing for inherited susceptibility to cancer.
Patient education video
Patient education brochures
Education for patients with cancer
PDF
Testing information for patients who have been diagnosed with cancer.
Education for patients who do not have cancer
PDF
Testing information for patients who have never had cancer.
Hereditary Breast Cancer brochure
PDF
Testing information for patients with a personal or family history of breast cancer.
Hereditary Colorectal Cancer brochure
PDF
Testing information for patients with a personal or family history of colorectal cancer.
Case studies
Susan: A CHEK2 case study
PDF
See how adding the STAT Breast Cancer Panel helped a carrier of a CHEK2 pathogenic variant decide on her surgical strategy and follow up.
Molly: A PALB2 case study
PDF
By combining the Oncotype DX Breast Recurrence Score® test with the STAT Breast Cancer Panel, a provider and their patient formed an ideal surgical approach.
Gwen: A BRCA1 case study
PDF
Learn how a patient decided to combine the OncoExTra® test with the Riskguard test to uncover information that would not only help herself, but her children and grandchildren as well.
Sample reports
Negative sample report
PDF
See an example of a negative Riskguard test report.
Positive BRCA1 sample report
PDF
See what the report could look like if your patient tests positive for a harmful gene change in BRCA1.
Uncertain sample report
PDF
An uncertain result means a change (referred to on a report as "variant of uncertain significance") was identified in a gene, but there is not enough data available yet to determine if that gene change actually increases cancer risk or if it is benign.
Results guides
Positive results guide
PDF
This guide aims to help with understanding a positive result and potential next steps.
Negative results guide
PDF
This guide aims to help with understanding a negative result.
Uncertain results guide
PDF
This guide aims to help with understanding a uncertain result and potential next steps.
Carrier results guide
PDF
This guide aims to help with understanding a carrier result and potential next steps.
Other resources
Patient identification resources
PDF
See which risk factors and diagnoses make the Riskguard test a fit for your patients with cancer.
Sample family share letter
PDF
Patients with a positive Riskguard test result might have family members at risk of carrying the same germline variant. A family share letter can help patients communicate their results to relatives.
Gene list
PDF
Riskguard is a multigene test that may impact clinical decision-making in common cancer types.
Specimen kits
Call customer care to request Riskguard test kits. We can send blood, saliva, or buccal test kits right to your office, or we can send a convenient at-home saliva test kit directly to your patient's address.*
Call +1 866-662-6897
Additional gene information
Gene info page
The Riskguard test evaluates 59 different genes. See our Gene Information page for more information about each and every one of them.
Sample letter of medical necessity
PDF
This is a resource for documenting medical necessity for possible use when testing medically appropriate patients to support coverage.
Ordering a test for your patients is fast and easy
Ordering a test for your patients is fast and easy
Order tests, access results, and receive updates through our Provider Hub .
References and footnotes
The Exact Sciences Riskguard test was developed, and its performance characteristics validated by an Exact Sciences laboratory following College of American Pathologists (CAP) and Clinical Laboratory Improvement Amendments (CLIA) regulations. The test is performed in Marshfield, WI at PreventionGenetics LLC, a wholly owned subsidiary of Exact Sciences. PreventionGenetics is accredited by CAP, certified under CLIA regulations, and qualified to perform high-complexity clinical laboratory testing. It has not been cleared or approved by the US Food and Drug Administration or other notified regulatory authority. Genomic Health, Inc., an Exact Sciences company, is the billing entity for the Riskguard test.